Sandra Perrone was born in Milan, Italy. Her background is in Russian and German literature studies.

She works in the music field since 1991, acting as artists' and ensembles' manager for some of the major European companies (Uhde & Harckensee MusikManagement Berlin, Musikfestspiele Potsdam Sanssouci und Nikolaisaal Potsdam, Stage Door Bologna, Walter Beloch Artists Management Milan, Il Giardino Armonico Milan). In 2013 she established her own company in Berlin.

Sandra Perrone speaks English, German, Italian, Russian and Bosnian/Croatian/Serbian.